Sex Differences in Patients with Heart Failure

Authors

Keywords:

heart failure, sex, female, mortality.

Abstract

Introduction: Heart failure is an important public health problem that has shown some sex differences in clinical, echocardiographic patterns and treatment modalities.

Objectives: To evaluate the influence of sex on the clinical presentation and prognosis of heart failure in hospitalized patients.

Methods: A retrospective study was conducted, including 153 patients with a diagnosis of heart failure admitted to the Institute of Cardiology and Cardiovascular Surgery of Havana, Cuba, in the period from January 2017 to December 2021.

Results: The history of heart failure and the acute chronic clinical form predominated in men, while in women the acute form and orthopnea were more frequent. Electrocardiographic and laboratory parameters were similar in both sexes. Heart failure with preserved ejection fraction prevailed in women, while left ventricular dilation was more frequent in men. Women underwent coronary angiography less frequently and there was no difference with respect to pharmacological treatment. Men had a greater number of rehospitalizations for heart failure, although women presented a tendency towards greater in-hospital mortality for this cause.

Conclusions: In those hospitalized for heart failure, women with preserved ejection fraction and high left ventricular filling pressures had a worse prognosis on admission with a tendency to higher in-hospital mortality.

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References

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Published

2024-04-19

How to Cite

1.
Natera Medina FJ, Jerez Castro AM, Hechavarría Pouymiró S. Sex Differences in Patients with Heart Failure. Rev. cuba. cardiol. cir. cardiovasc. [Internet]. 2024 Apr. 19 [cited 2025 Mar. 10];30:e2273. Available from: https://revcardiologia.sld.cu/index.php/revcardiologia/article/view/2273

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Original Articles