Gammagrafía de perfusión miocárdica versus otras técnicas en el diagnóstico de enfermedad arterial coronaria

Authors

  • Kenia M Padrón García Instituto de Cardiología y Cirugía Cardiovascular de Cuba
  • Amalia T Peix Glez Instituto de Cardiología y Cirugía Cardiovascular de Cuba
  • Lázaro Omar Cabrera Rodriguez
  • Norlan Reyes
  • Lidia Rodríguez-Nande
  • Leonardo Ferrero López
  • Deylis Chacón

Keywords:

Coronary artery disease, invasive coronary angiography, single photon emission computed tomography myocardial perfusion imaging, calcium scoring, stress test, diagnostic value

Abstract

Background: Myocardial perfusion imaging with SPECT is a widely established method for non-invasive evaluation of coronary artery stenosis. However, the diagnostic value of SPECT to detect coronary artery disease has not been well established. In our center, this technique was introduced in 2009. This is the first pilot study to investigate the diagnostic value of SPECT versus calcium scoring and stress test, in the detection of coronary artery disease, in our institution.  

Methods: A prospective, analytical study included fifty consecutive patients with diagnostic gated-SPECT and previous calcium scoring, who were submitted to an invasive coronary angiography. They underwent a gated-SPECT Myocardial Perfusion Imaging following a two-day protocol (stress-rest). We compared patients with and without significant coronary stenosis. The diagnostic security was studied by sensibility, specificity, predictive value, verisimilitude reason, accuracy proportion, Youden index and Kappa de Fleiss methods. The statistical signification was fixed in p<0.05.

Results: The calcium scoring value and all summed perfusion scores were significantly higher in the positive angiography group (p<0.000). The concordance (Kappa=0.12) and the efficiency (Youden=0.13) of the stress test compared to the angiography were poor. The calcium scoring had the highest specificity (82%), while the gated-SPECT had the highest sensitivity and negative predictive value (95% both), accuracy (82%) and concordance (Kappa=0.65) with the angiography. It also identified better patients with microvascular angina.  

Conclusions: The gated-SPECT had the best diagnostic security to determine coronary diseases versus the others non-invasive techniques.

Keywords: Coronary artery disease, invasive coronary angiography, single photon emission computed tomography myocardial perfusion imaging, calcium scoring, stress test, diagnostic value

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Author Biographies

Kenia M Padrón García, Instituto de Cardiología y Cirugía Cardiovascular de Cuba

Especialista en Cardiología y Medicina General Integral. Investigador agregado. Profesor asistente

Amalia T Peix Glez, Instituto de Cardiología y Cirugía Cardiovascular de Cuba

Especialista en Cardiología. Profesora e Investigadora Titular

Lázaro Omar Cabrera Rodriguez

Especialista en Cardiología y Medicina General Integral. Investigador agregado. Profesor asistente

Norlan Reyes

Especialista en Cardiología y Medicina General Integral. Municipio Jaruco

Lidia Rodríguez-Nande

Licenciada en Cibernética. Profesora e Investigadora y auxiliar

Leonardo Ferrero López

Especialista en Cardiología y Medicina General Integral. Investigador agregado. Profesor auxiliar

Deylis Chacón

Especialista en Cardiología. Hospital Luis Díaz Soto

How to Cite

1.
Padrón García KM, Peix Glez AT, Cabrera Rodriguez LO, Reyes N, Rodríguez-Nande L, Ferrero López L, et al. Gammagrafía de perfusión miocárdica versus otras técnicas en el diagnóstico de enfermedad arterial coronaria. Rev. cuba. cardiol. cir. cardiovasc. [Internet]. 2016 Jun. 16 [cited 2025 Mar. 12];22(1):25-33. Available from: https://revcardiologia.sld.cu/index.php/revcardiologia/article/view/627

Issue

Section

Cardiología Nuclear