C-reactive protein (CRP) and the classic risk factors in patients with stable coronary artery disease.

Authors

  • Flor de la Caridad Heres Álvarez Instituto de Cardiología y Cirugía Cardiovascular. La Habana. Cuba.
  • Amalia Peix González Instituto de Cardiología y Cirugía Cardiovascular. La Habana. Cuba.
  • Jorge Bacallao Gallestey Centro de Referencias de la Aterosclerosis de la Habana (CIRAH)
  • Omar González Greck Instituto de Cardiología y Cirugía Cardiovascular. La Habana. Cuba.
  • Roger Ravelo Dopico Hospital Militar Central "Dr. Carlos J. Finlay". La Habana, Cuba
  • Josanne Soto Matos Hospital Hermanos Ameijeiras. La Habana, Cuba
  • Amaury Flores Sánchez Instituto de Cardiología y Cirugía Cardiovascular. La Habana. Cuba.

Keywords:

C- reactive protein, classics risk factors, coronary artery disease

Abstract

Introduction: C-reactive protein (CRP) has emerged as an important indicator of risk for cardiovascular disease. Its predictive capacity could
be linked to its relation with the cardiovascular risk factors.
Objetive: To identify the relationship between C-reactive protein levels and the cardiovascular classic risk factors in patients with stable
coronary artery disease.
Methods: A total of 189 patients with angiographically determined stable coronary artery disease were studied. Sex, body mass index,
smoking, hypertension, diabetes mellitus, lipids and CRP were evaluated. The CRP levels were determined by a high sensitive method.
Results: The CRP values were higher in women as compared to men (3.25 vs. 2.25 mg/L). Although the CRP values were higher when either
cardiovascular risk factor was present, the most remarkable difference was for obese patients (3.88 vs. 1.54 mg/L). Positive correlations
were observed both between CRP and body mass index (r = 0.191, p= 0.003) and CRP and triglycerides concentrations (r= 0.138, p=
0.033), whereas a negative correlation was observed between CRP and HDL cholesterol (r= -0.150, p= 0.026). CRP levels increased with the
increasing number of cardiovascular risk factors.
Conclusions: Higher C-reactive protein levels are related to female sex and to classic cardiovascular risk factors, mainly obesity and
dislipidemia, in patients with stable coronary artery disease.

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Published

2015-02-19

How to Cite

1.
Heres Álvarez F de la C, Peix González A, Bacallao Gallestey J, González Greck O, Ravelo Dopico R, Soto Matos J, et al. C-reactive protein (CRP) and the classic risk factors in patients with stable coronary artery disease. Rev. cuba. cardiol. cir. cardiovasc. [Internet]. 2015 Feb. 19 [cited 2025 Apr. 6];20(4):Pag.217-225. Available from: https://revcardiologia.sld.cu/index.php/revcardiologia/article/view/547

Issue

Section

Cardiovascular prevention