Endomyocardial biopsies in patients with dilated myocardiopathy and myocarditis

Authors

  • Rosa María Coro
  • Carlos Cabrera
  • Virginia Capó
  • Carlos Domínguez
  • Flor Heres

Keywords:

CARDIOMYOPATHY, CONGESTIVE/pathology, MYOCARDITIS/pathology, MYOCARDIUM/pathology, BIOPSY, HEART VENTRICLE/pathology.

Abstract

The objective of this paper was to establish the correlation degree between the clinical status and the histological picture of patients with presumptive diagnosis of dilated myocardiopathy, or suspected of myocarditis, taking into account that the morphology and the contractile function of the myocardium should be closely related. A scoring system for qualitative parameters and ranges of values of quantitative variables was created to evaluate the clinical and histological aspects. Some clinical manifestations as well as the time of evolution and the electrocardiogram, telecardiogram and echocardiography variables were considered to evaluate the clinical status. Morphometric techniques were used in the histological study to rate the grades of interstitial fibrosis, cardiomyocytes hyplertrophy, and cellular damage. The correlation coefficient of Spearman between the clinical and histological scores was 0.97, significant at 1 %. This close morphofunctional relationship shows a high prognostic value for endomyocardial biopsy.

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Author Biographies

Rosa María Coro

Doctora en Ciencias Biológicas, Profesora Titular, Investigadora Auxiliar. Instituto de Cardiología y Cirugía Cardiovascular.

Carlos Cabrera

Doctor en Ciencias Biológicas, Profesora Titular, Investigadora Auxiliar. Instituto de Cardiología y Cirugía Cardiovascular.

Virginia Capó

Especialista de II Grado en Anatomía Patológica. Instituto "Pedro Kourí".

Carlos Domínguez

Especialista de II Grado en Anatomía Patológica. Hospital Clinicoquirúrgico "Hermanos Ameijeiras".

Flor Heres

Especialista de I Grado en Inmunología. Instituto de Cardiología y Cirugía Cardiovascular.

Published

2014-03-16

How to Cite

1.
Coro RM, Cabrera C, Capó V, Domínguez C, Heres F. Endomyocardial biopsies in patients with dilated myocardiopathy and myocarditis. Rev. cuba. cardiol. cir. cardiovasc. [Internet]. 2014 Mar. 16 [cited 2025 Apr. 30];12(2). Available from: https://revcardiologia.sld.cu/index.php/revcardiologia/article/view/433

Issue

Section

Research Methodology