Glycemia-triglyceride index as a predictor of in-hospital complications in patients with acute coronary syndrome
Keywords:
acute coronary syndrome, glycemia, triglycerides, insulin resistance.Abstract
Introduction: The glycemia-triglyceride index is considered a new marker of insulin resistance and is related to the development of cardiovascular diseases.
Objective: To evaluate the predictive capacity of the glycemia-triglyceride index for the occurrence of in-hospital complications in patients with acute coronary syndrome.
Methods: An observational, cohort study was conducted with 804 patients who were diagnosed with acute coronary syndrome between September 2018 and October 2021 in the Coronary Care Unit at the General Teaching Hospital “Enrique Cabrera Cossío”. To define the glycemia-triglyceride index performance, discrimination and calibration were assessed using the Statistical Package C and the Hosmer-Lemeshow test, respectively. The study ended with the onset of in-hospital complications. The study universe was divided according to the optimal cut point for this index.
Results: The optimal cut point of the index to predict mortality was 9.26. The incidence of in-hospital complications increased significantly in the group with a glycemia-triglyceride index ≥ 9.26. Logistic regression analysis showed that the index was an independent predictor of mortality. The multivariate model containing the index increased its predictive capacity (area under the curve 0.773; p < 0.001). Kaplan-Meier survival curves showed significant differences between the patient groups.
Conclusions: The increase of glycemia-triglyceride index is a strong independent predictor of in-hospital complications in acute coronary syndrome.
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